EPA Publishes Proposed Test Rule on Third Grouping of Chemicals


Source: SOCMA
Related Topics: Toxic Substances Control Act (TSCA) US Environmental Protection Agency

EPA is proposing a test rule under section 4(a)(1)(B) of the Toxic Substances Control Act (TSCA) that would require manufacturers, importers, and processors of certain high production volume (HPV) chemicals to conduct testing to obtain screening level data for health and environmental effects and chemical fate. The list of chemicals was generated using information primarily from the 2006 Inventory Update Rule (IUR) and a 2006 TSCA Preliminary Assessment Information Reporting (PAIR) rule issued for the HPV orphan chemicals. This proposed TSCA section 4(a) test rule addresses some of the 207 remaining ‘‘orphan’’ HPV chemicals that were placed on the Priority Testing List by the Interagency Testing Committee (ITC), many of which no longer support TSCA section 4(a) findings.  The number of chemicals listed in this grouping is 29.  Of the 29 chemicals listed, 20 of them involved a ‘‘substantial exposure’’ finding for consumers, which is noteworthy. 

The list of chemicals is below:

CAS No.       Chemical Name
83–41–0       Benzene, 1,2-dimethyl-3-nitro-
96–22–0       3-Pentanone
98–09–9       Benzenesulfonyl chloride
98–56–6       Benzene, 1-chloro-4-(trifluoromethyl)-
111–44–4     ’Ethane, 1,1’-oxybis[2-chloro-
127–68–4     Benzenesulfonic acid, 3-nitro-, sodium salt (1:1)
506–51–4     1-Tetracosanol
506–52–5     1-Hexacosanol
515–40–2     Benzene, (2-chloro-1,1-dimethylethyl)-
2494–89–5   Ethanol, 2-[(4-aminophenyl)sulfonyl]-, 1-(hydrogensulfate)
5026–74–4   2-Oxiranemethanamine, N-[4-(2-oxiranylmethoxy)phenyl]-N-(2-oxiranylmethyl)-
22527–63–5   Propanoic acid, 2-methyl-, 3-(benzoyloxy)-2,2,4-trimethylpentyl ester
24615–84–7   2-Propenoic acid, 2-carboxyethyl ester
25321–41–9   Benzenesulfonic acid, dimethyl-
25646–71–3   Methanesulfonamide, N-[2-[(4-amino-3-methylphenyl)ethylamino]ethyl]-, sulfate (2:3)
52556–42–0   1-Propanesulfonic acid, 2-hydroxy-3-(2-propenyloxy)-, sodium salt (1:1)
61788–76–9    Alkanes, chloro
65996–79–4    Solvent naphtha (coal)
65996–82–9    Tar oils, coal
65996–89–6    Tar, coal, high-temperature
65996–92–1    Distillates (coal tar)
68082–78–0    Lard, oil, Me esters
68187–57–5    Pitch, coal tar-petroleum
68442–60–4    Acetaldehyde, reaction products with formaldehyde, by-products from
68610–90–2    2-Butenedioic acid (2E)-, di-C8–18-alkyl Esters
68988–22–7    1,4-Benzenedicarboxylic acid, 1,4-dimethylester, manuf. of, by-products from
70693–50–4    Phenol, 2,4-bis(1-methyl-1-phenylethyl)-6-[2-(2-nitrophenyl)diazenyl]-
72162–15–3    1-Decene, sulfurized
73665–18–6    Extract residues (coal), tar oil alk., naphthalene distn. Residues

The EPA solicits comments on the potential exposures to workers and consumers, and additional information pertaining to the amount of environmental release of the chemical substances identified in this proposed rule.  Comments are also being sought on the availability of existing studies on the SIDS endpoints and other testing approaches. Continuing, the attainable test substance purity was brought up as an area for comment. Finally, electronic submission of a final test report would be required after this rule goes final and comments are sought on this.  Comments must be received on or before May 26, 2010.  Click here to access the proposed rule.

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